首页> 外国专利> Use for the treatment and prevention of atherosclerosis protein-peptide complex (hereinafter BOD) derived from the embryonic neural tissue or quick-frozen fetal brain agricultural ungulates affecting the reverse transport of cholesterol from the vessel wall and the profile of the activation of monocytes in patients with severe atherosclerosis main vessels or with a predisposition to cardiovascular disease and a method of prevention and treatment of patients with atherosclerosis and arterial disease caused by atherosclerosis of the main and peripheral vessels of the brain, heart, blood vessels of the lower extremities and the aorta (two options)

Use for the treatment and prevention of atherosclerosis protein-peptide complex (hereinafter BOD) derived from the embryonic neural tissue or quick-frozen fetal brain agricultural ungulates affecting the reverse transport of cholesterol from the vessel wall and the profile of the activation of monocytes in patients with severe atherosclerosis main vessels or with a predisposition to cardiovascular disease and a method of prevention and treatment of patients with atherosclerosis and arterial disease caused by atherosclerosis of the main and peripheral vessels of the brain, heart, blood vessels of the lower extremities and the aorta (two options)

机译:用于治疗和预防源自胚胎神经组织或速冻胎儿脑农用有蹄类动物的动脉粥样硬化蛋白-肽复合物(以下称BOD),可影响胆固醇从血管壁的反向转运以及患者单核细胞的活化情况患有严重动脉粥样硬化主血管或易患心血管疾病的人,以及一种预防和治疗因脑,心脏,下肢血管和主动脉的主动脉和外周血管粥样硬化而引起的动脉粥样硬化和动脉疾病的方法(两个选项)

摘要

1. The use for the treatment and prevention of atherosclerosis protein-peptide complex (hereinafter - BOD) derived from fetal nervous tissue or from a fetal brain quick-frozen agricultural ungulates affecting the reverse transport of cholesterol from the vessel wall and the profile of the activation of monocytes in patients with severe atherosclerosis backbone vessels or predisposed to cardiovascular disease, including negatively charged, neutral proteins and polypeptides, with molecular weights from 0.5 to 200 kDa or in conjunction with it polynucleotides as Na-salt of DNA isolated from sturgeon milt or salmon fish, in the form of protein-polynucleotide-peptide complex for the prophylaxis and treatment of patients with atherosclerosis and arterial disease, caused by atherosclerosis of the main and peripheral vessels of the brain, heart, blood vessels of the lower extremities, and aortic administered in a therapeutically effective daily and course doses administered parenterally or intranasally, and regulating cholesterol metabolism, cholesteryl ester, triglycerides, phospholipids subendothelial connective tissue and smooth muscle cells of arterial sosudov.2. A method for preventing and treating atherosclerotic patients arterial vessels and diseases caused by atherosclerosis main and peripheral vessels of the brain, heart, blood vessels of the lower limbs and the aorta, comprising administering to a patient a pharmaceutical preparation comprising a protein-peptide complex (hereinafter - BOD) in combination with a pharmaceutically acceptable carrier or parenterally intro
机译:1.用于治疗和预防源自胎儿神经组织或源自胎儿脑速冻农用有蹄类动物的动脉粥样硬化蛋白-肽复合物(以下称BOD),其影响胆固醇从血管壁的反向转运以及其轮廓重度动脉粥样硬化主干血管或易患心血管疾病的患者中单核细胞的活化,包括分子量为0.5至200 kDa的带负电荷的中性蛋白质和多肽,或与之结合的多核苷酸,如从st鱼糜或鲑鱼鱼,蛋白质-多核苷酸-肽复合物形式,用于预防和治疗由脑,下肢血管和主动脉的主要和周围血管的动脉粥样硬化引起的动脉粥样硬化和动脉疾病的患者以治疗有效的每日剂量和非肠道或完整剂量给药鼻腔调节胆固醇的代谢,胆固醇酯,甘油三酸酯,磷脂的内皮下结缔组织和动脉sosudov的平滑肌细胞。2。一种预防和治疗动脉粥样硬化患者的动脉血管和由脑,心脏,下肢血管和主动脉的动脉粥样硬化主要和周围血管引起的疾病的方法,包括向患者施用包含蛋白质-肽复合物(下文-BOD)与可药用载体的组合或肠胃外

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