COMPOSITIONS COMPRISING MIR-143 AND/OR MIR-145 OR (AN) EXPRESSION VECTOR(S) THEREOF, FOR USE AS MEDICAMENTS

摘要

The present invention relates to a microparticle comprising a functional microRNA/siRNA and application thereof. Specifically, disclosed is a use of a functional microRNA and/or siRNA, which is used to prepare a composition applied to a mammal. After the composition is applied, the microparticle is formed in a first part in an animal, and transported to a second part, which thereby improves physiological status of the second part or heals a disease of the second part. The second part is different from the first part. The use is beneficial for optimizing a dosing manner of the functional microRNA and/or siRNA.