COMPOSITION COMPOSED OF CEFTRIAXONE SODIUM AND SULBACTUM SODIUM

摘要

The present invention provides a composition composed of ceftriaxone sodium and sulbactam sodium, a pharmaceutical composition comprising the same and the application thereof. The composition is characterized in that diffraction peaks at specific angles are included in the X-ray powder diffraction analysis spectrum. The pharmaceutical composition according to the present invention have better antibacterial activity and stability compared with known compositions, and are thus very suitable for the treatment of bacterial infections, especially for the treatment of refractory urogenital system infections caused by Neisseria gonorrhoeae which is drug-resistance to a variety of antibiotics (β-lactams, tetracyclines, macrolides, fluoroquinolones and aminoglycosides).