Method for producing stable injection solution containing palonosetron

摘要

PROBLEM TO BE SOLVED: To address the problem that conventional liquid formulations for injection containing palonosetron required, as a stabilizer, a chelator (edetate sodium hydrate) which could lead to the formation of chelates with metal components within the body, thus a liquid formulation for injection containing palonosetron that does not contain a chelator is desired.SOLUTION: By using specific buffers in the liquid formulation for injection containing palonosetron, it has become possible to provide a liquid formulation for injection containing palonosetron without including chelators.SELECTED DRAWING: None