Simultaneous estimation of respiratory mechanics and patient effort by parameter optimization

摘要

The respiratory variable is estimated for each breath from the airway pressure data and the airway flow rate data acquired by the airway pressure sensor and the airway flow rate sensors (20, 22). The respiration detector (28) detects the respiration interval. A breath-by-breath respiratory variable estimator (30) correlates airway pressure data and airway flow data over the detected breathing interval with airway pressure, airway flow, and tidal parameterized respiratory muscle pressure profile (40, 42). To generate an optimized parameter value for a tidal parameterized respiratory muscle pressure profile. Respiratory muscle pressure is estimated as a tidal respiratory parameterized respiratory muscle pressure profile with optimized parameter values as a function of time over the detected respiratory interval, eg trending on the display device (26, 36) It may be displayed as a line, or it may be integrated (32) to generate respiratory work (WoB) for use in adjusting the settings of the ventilator (10). .