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A method for rapid and sensitive detection of hot spot mutations
A method for rapid and sensitive detection of hot spot mutations
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机译:一种快速灵敏地检测热点突变的方法
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摘要
Methods that rapidly, sensitively, and specifically detect mutations in IDH1/2 and the TERT promoter employ amplification of particular portions of the genes that experience frequent and exquisitely localized mutations. The ability to distinguish between sequences that differ only by one nucleotide and which may be present in very low ratios is essential for such an assay.
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