首页> 中文期刊> 《上海交通大学学报:医学英文版》 >A RAPID AND SENSITIVE METHOD FOR DETECTION OF ARYLSULFATASE ACTIVITIES

A RAPID AND SENSITIVE METHOD FOR DETECTION OF ARYLSULFATASE ACTIVITIES

         

摘要

正 Conventional colorimetric methods for determination of arylsulfatase activities are insensitive for microassays. In this study a rapid and sensitive fluorogenic technique was used with issues of the normal levels of arylsulfatase A and B activities in leukocytes. In addition, 2 cases of genetic lysosomal storage diseases were confirmatively diagnosed, one as MLD, the other as MLS, and a third case highly suspected clinically as MLS was finally excluded by this method.

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