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1AP E3 ligase directed proteolysis targeting chimeric molecules

机译:1AP E3连接酶定向蛋白水解靶向嵌合分子

摘要

The present invention relates to compounds, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, compositions and medicaments, for example as inhibitors of the activity of RIP2 kinase, including degrading RIP2 kinase, the treatment of diseases and conditions mediated by the RIP2 kinase, in particular for the treatment of inflammatory diseases or conditions.
机译:本发明涉及包含所述化合物的化合物,组合物,组合物和药物及其制备方法。本发明还涉及所述化合物,组合,组合物和药物的用途,例如作为RIP2激酶活性的抑制剂,包括降解RIP2激酶,用于治疗由RIP2激酶介导的疾病和病症,特别是用于治疗的用途。炎性疾病或状况。

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