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Microorganism producing lactic acid and method for producing lactic acid using same

机译:微生物产生乳酸和使用该微生物产生乳酸的方法

摘要

The present application relates to a microorganism of the genus Saccharomyces producing lactic acid and a method for preparing lactic acid using the same. More specifically, the present application relates to a microorganism of the genus Saccharomyces producing lactic acid, wherein the microorganism is modified to weaken or inactivate the activity of pyruvate decarboxylase (PDC) compared to its endogenous activity, to introduce the activity of ATP-citrate lyase (ACL), and to enhance pyruvate biosynthetic pathway compared to its endogenous biosynthetic pathway, and a method for producing lactic acid using the microorganism.
机译:本发明涉及产酿酒酵母属乳酸的微生物及其制备乳酸的方法。更具体地,本申请涉及产<!-SIPO ->酿酒酵母(Saccharomyces)的乳酸的微生物,其中与该微生物的内源活性相比,该微生物被修饰以减弱或灭活丙酮酸脱羧酶(PDC)的活性。与其内源性生物合成途径相比,具有增强柠檬酸ATP裂解酶(ACL)活性,增强丙酮酸生物合成途径的能力,以及利用该微生物生产乳酸的方法。

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