A cloud-based encryption machine key injection system includes at least one key injection sub-system including a key generation device and a quantum key distribution device connected with the key generation device, and a cloud-based encryption machine hosting sub-system including an encryption machine carrying a virtual encryption device and a quantum key distribution device connected with the encryption machine. The key injection sub-system and the encryption machine hosting sub-system are connected with each other through their respective quantum key distribution devices. The key generation device may generate a root key component of the virtual encryption device and transmit the root key component to the encryption machine. The encryption machine may receive root key components from one or more key generation devices and synthesize a root key of the virtual encryption device in accordance with the received root key components.
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