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Delivery System That Utilizes Liposomal or Emulsion Vehicles

机译:利用脂质体或乳剂载体的输送系统

摘要

The present invention discloses a liposomal delivery vehicle that includes lignite extract (or humic or fulvic acid) as a complexing agent to improve the stability and ultradeformability of the liposomal vehicle, thereby improving bioavailability. An emulsion delivery vehicle that includes lignite extract (or humic or fulvic acid) as the complexing agent is also disclosed. These improved delivery vehicles enhance the pharmacokinetic profiles of the active ingredients and reduce the quantities needs for therapeutic effect.
机译:本发明公开了脂质体输送载体,其包括褐煤提取物(腐殖酸或黄腐酸)作为络合剂,以改善脂质体载体的稳定性和超可变形性,从而改善生物利用度。还公开了包含褐煤提取物(或腐殖酸或黄腐酸)作为络合剂的乳液输送载体。这些改进的递送载体增强了活性成分的药代动力学特征,并减少了治疗效果的需求量。

著录项

  • 公开/公告号US2019110988A1

    专利类型

  • 公开/公告日2019-04-18

    原文格式PDF

  • 申请/专利权人 LEMULSA TECHNOLOGIES INC.;

    申请/专利号US201715786032

  • 发明设计人 TYLER BARRETT;CHARLES SLY;

    申请日2017-10-17

  • 分类号A61K9/127;A61K47/46;

  • 国家 US

  • 入库时间 2022-08-21 12:09:43

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