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SELECTIVE ACTIVATION OF CORTEX USING BENT MICRO-WIRES TO MAGNETICALLY STIMULATE NEURONS

机译:利用弯曲微线对神经元进行磁激活神经的选择性激活

摘要

Disclosed are micro-wire stimulators that magnetically stimulate nearby cells and/or their processes (e.g., nerve fiber, axons, dendrites, etc.). The micro-wire includes one or more bends. The micro-wire stimulator can facilitate the creation of stronger field gradients in one direction with much smaller gradients in orthogonal directions, allowing for selective targeting, or avoiding, of specific cell types within a targeted region. The bent micro-wire stimulator may be implanted into the cortex of the brain to selectively stimulate nearby neural cells having a particular orientation relative to the stimulator. A tip portion of the micro-wire may be rounded, or it may have corners forming other suitable geometric shapes.
机译:公开了微线刺激器,其磁刺激附近的细胞和/或其过程(例如,神经纤维,轴突,树突等)。所述微线包括一个或多个弯曲。微线刺激器可以促进在一个方向上产生更强的场梯度,而在正交方向上产生更小的梯度,从而允许选择性地靶向或避免靶向区域内的特定细胞类型。弯曲的微线刺激器可以被植入到大脑皮层中,以选择性地刺激相对于刺激器具有特定取向的附近神经细胞。微线的尖端部分可以是圆形的,或者可以具有形成其他合适的几何形状的角。

著录项

  • 公开/公告号US2019099609A1

    专利类型

  • 公开/公告日2019-04-04

    原文格式PDF

  • 申请/专利权人 THE GENERAL HOSPITAL CORPORATION;

    申请/专利号US201716086584

  • 发明设计人 SEUNGWOO LEE;SHELLEY FRIED;

    申请日2017-03-22

  • 分类号A61N2/00;A61N2/02;

  • 国家 US

  • 入库时间 2022-08-21 12:04:42

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