Summary "Method of Preparation of Carfentrazone-Ethyl" A method of preparation of carfentrazone-ethyl comprises the steps of: reacting 1- (5-amino-4-chloro-2-fluorophenyl) -4-difluoromethyl-3-methyl-1h- 1,2,4-triazol-5-one with acrylic acid via a diazo arylation reaction to give 2-chloro-3- [2-chloro-5- [4- (difluoromethyl) -4,5 acid -dihydro-3-methyl-5-oxo-1h-1,2,4-triazol-1-yl] -4-fluorophenyl] propionic acid and reacting 2-chloro-3- [2-chloro-5- [ 4- (difluoromethyl) -4,5-dihydro-3-methyl-5-oxo-1h-1,2,4-triazol-1-yl] -4-fluorophenyl] propionic acid with ethanol via an esterification reaction on the presence of an acid catalyst to generate carfentrazone-ethyl.
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