首页> 外国专利> ISATIN DERIVATIVE COMPOUND, USE OF COMPOUND, AND METHODS FOR AIDS TREATMENT, TREATMENT OF HBV INFECTION AND TREATMENT OF HIV AND HBV COINFECTION.

ISATIN DERIVATIVE COMPOUND, USE OF COMPOUND, AND METHODS FOR AIDS TREATMENT, TREATMENT OF HBV INFECTION AND TREATMENT OF HIV AND HBV COINFECTION.

机译:ISATIN衍生物,化合物的使用以及艾滋病的治疗方法,HBV感染的治疗以及HIV和HBV感染的治疗。

摘要

The present invention relates to hiv inhibitor compounds consisting of isatin derivatives of formulas i, ii and iii as shown below (formulas i, ii and iii) where in formulas i, ii and iii, r1 is selected from h, ch3 or cl r2 is selected from one of the following radicals: zidovudine, amprenavir or an acyclic phosphonate chain, shown below. The present invention also consists of the use and method of treatment using the compounds of formulas i, ii and iii. The compounds of the present invention are also used to treat an infection caused by hbv or coinfection caused by hiv and hbv.
机译:本发明涉及由下式(式i,ii和iii)所示的式i,ii和iii的isatin衍生物组成的hiv抑制剂化合物,其中在式i,ii和iii中,r1选自h,ch3或c1。选自下列基团之一:齐多夫定,氨普那韦或无环膦酸酯链,如下所示。本发明还包括使用式i,ii和iii的化合物的用途和治疗方法。本发明的化合物还用于治疗由HBV引起的感染或由HIV和HBV引起的共感染。

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