首页> 外国专利> (s)-4-(8-amino-3-(1-but-2-ynoylpyrrolidin-2-yl) imidazo 1,5-apyrazin-1-yl)-n-(pyridin-2-yl)benzamide as btk – inhibitor

(s)-4-(8-amino-3-(1-but-2-ynoylpyrrolidin-2-yl) imidazo 1,5-apyrazin-1-yl)-n-(pyridin-2-yl)benzamide as btk – inhibitor

机译:(s)-4-(8-氨基-3-(1-丁-2-炔酰基吡咯烷-2-基)咪唑并[1,5-a]吡嗪-1-基)-n-(吡啶-2-基)苯甲酰胺作为btk –抑制剂

摘要

The present invention relates to 6-5 membered fused pyridine ring compounds according to formula Ior a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of 6-5 membered fused pyridine ring compounds according to formula I in the treatment of Bruton's Tyrosine Kinase (Btk) mediated disorders.
机译:本发明涉及式I的6-5元稠合吡啶环化合物或其药学上可接受的盐,或涉及包含这些化合物的药物组合物及其在治疗中的用途。特别地,本发明涉及式I的6-5元稠合吡啶环化合物在治疗布鲁顿酪氨酸激酶(Btk)介导的疾病中的用途。

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