首页> 外国专利> (S)-4-(8-AMINO-3-(1-(BUT-2-YNOYL)PYRROLIDIN-2-YL)IMIDAZO1,5-APYRAZIN-1-YL)-2-METHOXY-N-(PYRIDIN-2-YL)BENZAMIDE AS BTK-INHIBITOR

(S)-4-(8-AMINO-3-(1-(BUT-2-YNOYL)PYRROLIDIN-2-YL)IMIDAZO1,5-APYRAZIN-1-YL)-2-METHOXY-N-(PYRIDIN-2-YL)BENZAMIDE AS BTK-INHIBITOR

机译:(S)-4-(8-AMINO-3-(1-(BUT-2-YNOYL)吡咯烷基-2-YL)咪唑啉[1,5-A]吡嗪-1-基)-2-甲氧基-N- (PYRIDIN-2-YL)苯甲酰胺作为BTK抑制剂

摘要

The present invention relates to 6-5 membered fused pyridine ring compounds according to formula Ior a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of 6-5 membered fused pyridine ring compounds according to formula I in the treatment of Bruton's Tyrosine Kinase (Btk) mediated disorders.
机译:本发明涉及式I的6-5元稠合吡啶环化合物 <图像文件=“ IMGA0001.GIF” he =“ 57” imgContent =“ chem” imgFormat =“ GIF” wi =“ 37” /> 或其药学上可接受的盐或包含这些化合物的药物组合物及其在治疗中的用途。特别地,本发明涉及式I的6-5元稠合吡啶环化合物在治疗布鲁顿酪氨酸激酶(Btk)介导的疾病中的用途。

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