Trans-(4S,5R,6S)-4-(benzod1',3'-dioxol-5'-yl)-5-(1-iodoethyl)-dihydrofuran-2-one and method for obtaining it

摘要

the application relates to optically active beta - (benzo [d] [1 ', 3') - dioksol - 5 '- yl) -? - jodo -? lactone of formula 1 shown in figure and the method thereof.method for optically active beta - (benzo [d] [1 ', 3') - dioksol - 5 '- yl) -? - jodo -? lactone is that (2r, 3e) - 4 - (benzo [d] [1 ', 3') - dioksol - 5 '- yl) - shoe - 3 - en - 2 - ol is carried out by trzyetapowej synthesis in a mixture jodolaktonu00f3w, which subsequently by column chromatography is excreted in the pure form trans - (4s, 5r, 6s) - 4 - (benzo [d] [1',3 '] - dioksol - 5' - yl) - 5 - (1 - jodoetylo) - dihydrofuran-2 - he. optically active beta - (benzo [d] [1 ', 3' - 5 'dioksol) - yl) -? - jodo -? - lactone of formula 1 may find application in pharmacy as a relationship with antynowotworowym.