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IMMUNOGLOBULIN G (IgG) CONCENTRATE DEPLETED OF ANTI-A AND ANTI-B ANTIBODIES AND OF POLYREACTIVE IgGs
IMMUNOGLOBULIN G (IgG) CONCENTRATE DEPLETED OF ANTI-A AND ANTI-B ANTIBODIES AND OF POLYREACTIVE IgGs
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机译:免疫球蛋白G(IgG)浓缩的抗A和抗B抗体以及多反应性IgG
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摘要
Immunoglobulin G (IgG) concentrate for therapeutic use, comprises anti-A and anti-B antibodies compliant with a negative result in the indirect Coombs test in vitro. An independent claim is included for obtaining the IgG concentrate comprising preparing an IgG concentrate by ethanolic fractionation and/or chromatographic separation, in association with a viral inactivation, immunoaffinity chromatography by percolation of the IgG concentrate on a support mixture of which matrices are grafted with oligosaccharide groups antigenically similar to blood groups A and B, and filtering for elimination of virus and/or particles of size higher than 20 nm. ACTIVITY : Antimicrobial; Immunosuppressive. MECHANISM OF ACTION : None given.
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