G immunoglobulin concentrate (IgG) depleted in anti-A and anti-B antibodies, and in polyreactive IgG

摘要

Therapeutic concentrate of immunoglobulins G (IgG), characterized in that it has respective contents in anti-A and anti-B antibodies conforming to a negative result to the indirect Coombs test in vitro, at 1/64 dilution, carried out with a initial concentration IgG solution carried at 30g / l and a residual polyreactive IgG content comprised between 0.01% and 0.1%, with respect to the total IgG content, said residual polyreactive IgG content being measured by ELISA using the albumin antigen modified by dinitrophenyl groups (Albumin DNP).