Method for obtaining extract from Cochlospermum angolense with anti-tumor activity and application of the extract from Cochlospermum angolense in treatment of melanoma

摘要

The purpose of the notification is to obtain an extract of Cochlospermum angolensis (Borututu),which consists of the powder being coated with chloroform, preferably twice, each time for 12 -72 hours preferably 48 hours, using favourable quantities first 1:20 and then 1:10, followed by a chloroform macerate or a combined macerate evaporating ra at a temperature not exceeding 40oC and the dry residue (SP) is mixed with silicon gel in a weight ratio from 1:1 to 1:100 preferably 1:10 and further extracted in the liquid /body system using hexane or ethyl acetate and /or a favourable mixture thereof. e in proportion 1:1,After evaporation of the eluent, a fraction with high anti -cancer activity is obtained. An extract of Cochlospermum angolense Welw is also included. ex Olive. Son. Maximilianea angolensis (Welw). ex Oliv.),obtained by two -stage extraction: maceration with chloroform and extraction with hexane or ethyl acetate and /or a mixture thereof (Ex2) and use of this extract in the treatment of black.