METHOD FOR DETECTION AND QUANTIFICATION OF ARTERIAL CALCIFICATION

摘要

Use of tissue composition and anthropomorphic measures in a method for the detection and quantification of arterial calcification in an organ is described for disease risk prediction and stratification. A radiographic image of an organ is transformed quantitatively to a tissue composition map indicating a total amount of organ tissue; a calcification map is generated indicating position in the tissue composition map of calcified tissue; calcification free tissue composition map is generated from the tissue composition map using the position of calcified tissue in the calcification map; a vessel map of the position of vessels in the tissue composition map is generated; and the vessel map is combined with the calcification map to generate a map of vessel calcification indicating the position of calcified vessels in the tissue composition map. Scores are based on arterial calcification in a breast which indicates disease in the breast and other organs.