首页> 外国专利> A RAPID HIGH YIELDING PURIFICATION PROCESS FOR NEISSERIA MENINGITIDIS SEROGROUP X CAPSULAR POLYSACCHARIDE

A RAPID HIGH YIELDING PURIFICATION PROCESS FOR NEISSERIA MENINGITIDIS SEROGROUP X CAPSULAR POLYSACCHARIDE

机译：猪奈瑟氏球菌血清X胶囊多糖的快速高产纯化工艺

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摘要

The present invention discloses a rapid high yielding purification process for Neisseria meningitidis serogroup X capsular polysaccharide. The capsular polysaccharide of present invention is capable of being used in the production of economical monovalent capsular polysaccharide or polysaccharide protein conjugate vaccine or multivalent combination vaccines as well as a diagnostic tool against meningococcal serogroup X infections. The process employs simple salts and lesser quantity of ethanol. The process is rapid, economic and scalable with high yield of purified polysaccharide of Neisseriameningitidis serogroup X.

机译：本发明公开了一种脑膜炎奈瑟氏球菌血清X型荚膜多糖的快速高产纯化方法。本发明的荚膜多糖能够用于生产经济的单价荚膜多糖或多糖蛋白结合疫苗或多价组合疫苗，以及针对脑膜炎球菌X血清群感染的诊断工具。该方法使用简单的盐和较少量的乙醇。该过程快速，经济且可扩展，并具有高收率的奈瑟氏球菌 脑膜炎球菌血清群X的纯化多糖。 展开▼

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公开/公告号WO2019003239A1

专利类型

公开/公告日2019-01-03

原文格式PDF

申请/专利权人 MSD WELLCOME TRUST HILLEMAN LABORATORIES PVT. LTD.;
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申请/专利号WO2018IN50256

发明设计人 SHARMA SANDEEP;KUMAR NITIN;HANIF SARMAD;GILL DAVINDER;
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申请日2018-04-26

分类号C12P19/04;A61K39/095;C07K14/22;C12N1/20;C08B37;

国家 WO

入库时间 2022-08-21 11:57:31

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1. 一种快速高效纯化血清群X脑膜炎奈瑟菌荚膜多糖的工艺 [P] . 中国专利： CN110892076A . 2020-03-17

2. 含重组菌毛蛋白的抗淋病奈瑟氏球茵或脑膜炎奈瑟氏球菌的疫苗 [P] . 中国专利： CN1245512C . 2006.03.15

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5. STRAIN OF BACTERIA NEISSERIA MENINGITIDIS OF SEROGROUP B - A PRODUCER OF CAPSULAR POLYSACCHARIDES AND POLYSACCHARIDE-PROTEIN COMPLEX [P] . SU1708846A1 . 1992-01-30

机译：血清球菌B的奈瑟菌的菌株-荚膜多糖和多糖蛋白复合物的产生者。

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