USE OF METADOXINE AS HEPATOPROTECTOR IN THE TREATMENT OF HEPATIC TOXICITY INDUCED IN PATIENTS TREATED WITH METHOTREXATE

摘要

The object of the present invention is the use of Metadoxine as hepatoprotector against hepatic toxicity induced in patients undergoing treatment with Methotrexate, preferably in patients affected by rheumatoid arthritis. The invention further relates to the use of Metadoxine administered in combination with Methotrexate, in the treatment of rheumatoid arthritis.