首页> 外国专利> COMPOSITIONS AND METHODS FOR PREVENTING THE RECURRENCE OF ATRIAL FIBRILLATION AND/OR ATRIAL FLUTTER IN A HUMAN

COMPOSITIONS AND METHODS FOR PREVENTING THE RECURRENCE OF ATRIAL FIBRILLATION AND/OR ATRIAL FLUTTER IN A HUMAN

机译:预防人类房颤和/或房扑复发的组合物和方法

摘要

Disclosed are compositions and methods for preventing the recurrence of an episode of atrial fibrillation and/or atrial flutter without also inducing torsades de pointes or ventricular fibrillation in a human patient that has previously undergone an episode of atrial fibrillation and/or atrial flutter. Such methods include orally consuming on a daily basis for each of a first plurality of days a single unitary dosage form containing about 50 mg to about 100 mg of vanoxerine, or an equivalent amount of a salt thereof, and one or more pharmaceutically acceptable inert excipients, and then not orally consuming any vanoxerine on a daily basis for a second plurality of days
机译:公开了在先前还经历过心房颤动和/或心房扑动的人类患者中,预防房颤和/或心房颤动的发作而又不引起尖端扭转性室速或心室纤颤的组合物和方法。此类方法包括在头几天的每一天中每天口服摄入单一单剂型,该单剂型包含约50 mg至约100 mg的vanoxerine或等量的盐以及一种或多种药学上可接受的惰性赋形剂,然后连续第二天每天不口服任何钒氧

著录项

  • 公开/公告号WO2019147890A1

    专利类型

  • 公开/公告日2019-08-01

    原文格式PDF

  • 申请/专利权人 BROWN ARTHUR M.;BROWN ARTHUR M.;

    申请/专利号WO2019US15080

  • 发明设计人 BROWN ARTHUR M.;BROWN ARTHUR M.;

    申请日2019-01-25

  • 分类号A61K31/495;C07D241/04;A61P9;

  • 国家 WO

  • 入库时间 2022-08-21 11:53:46

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