Use of bispecific antibodies that recognize coagulation factor IX and / or activated coagulation factor IX and coagulant factor X and / or activated coagulant factor X

摘要

It is an object of the present invention to provide an effective pharmaceutical composition or dosing regimen for the prevention and / or treatment of bleeding, diseases accompanied by bleeding, or diseases caused by bleeding. The present inventors have found that a composition comprising a bispecific antigen binding molecule that recognizes (a) a factor of Factor IX and / or an activated blood coagulation factor IX and (b) a factor of coagulant X and / It has been found that by administering the pharmaceutical composition according to a predetermined dosing regimen, the bleeding, the disease accompanying bleeding, or the disease caused by bleeding can be prevented and / or treated more effectively.