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Novel Insights and New Developments Regarding Coagulation Revealed by Studies of the Anti-Factor IXa (Activated Factor IX)/Factor X Bispecific Antibody, Emicizumab

机译：关于抗因子IXA（活性因子IX）/因子x双特异性抗体，Emicizumab的抗凝血的新颖见解和新的发展

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Koji Yada; Keiji Nogami;
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1. Emicizumab, the bispecific antibody to factors IX/IXa and X/Xa, potentiates coagulation function in factor XI-deficient plasma in vitro [J] . Minami H., Nogami K., Yada K., Journal of thrombosis and haemostasis: JTH . 2019,第1期

机译：Emicizumab，对因子IX / IXA和X / XA的双特异性抗体，增强凝血功能在体外因子XI缺陷血浆中的凝血功能
2. An anti-factor IXa/factor X bispecific antibody, emicizumab, improves ex vivo coagulant potentials in plasma from patients with acquired hemophilia A [J] . Analysis and applications . 2020,第4期

机译：抗因子IXA /因子X双特异性抗体，Emicizumab，从获得的血友病患者中改善了血浆中的蜕皮凝血潜力
3. Factor Villa-mimetic cofactor activity of a bispecific antibody to factors IX/IXa and X/Xa, emicizumab, depends on its ability to bridge the antigens [J] . Kitazawa Takehisa, Esaki Keiko, Tachibana Tatsuhiko, Thrombosis and Haemostasis: Journal of the International Society on Thrombosis and Haemostasis . 2017,第7期

机译：因子villa-ixa和x / xa，emicizumab的双特异性抗体的模拟型辅助acoctors活性的双特异性抗体的活性取决于其桥接抗原的能力
4. IMMUNOLOGICAL CHARACTERIZATION OF ANTI-FACTOR VIII ANTIBODIES BY A SANDWICH- ELISA AND THE BIA-TECHNOLOGY [C] . G.IANNONE, P.G.DAVOLI, A.TRALDI, Sensors and Microsystems . 2002

机译：夹心ELISA和BIA技术对抗因子VIII抗体的免疫学鉴定
5. The active site of membrane-bound blood coagulation factor IXa: Its location above the membrane surface and its conformational sensitivity to the factor VIIIa cofactor. [D] . Mutucumarana, Vasantha Prem. 1994

机译：膜结合凝血因子IXa的活性部位：其在膜表面上方的位置及其对因子VIIIa辅因子的构象敏感性。
6. Factor VIIIa-mimetic cofactor activity of a bispecific antibody to factors IX/IXa and X/Xa emicizumab depends on its ability to bridge the antigens [O] . Takehisa Kitazawa, Keiko Esaki, Tatsuhiko Tachibana, -1

机译：针对因子IX / IXa和X / Xa的双特异性抗体Emicizumab的因子VIIIa模拟辅助因子活性取决于其桥接抗原的能力
7. Modified clot waveform analysis to measure plasma coagulation potential in the presence of the anti-factor IXa/factor X bispecific antibody emicizumab: comment [O] . T. Matsumoto, H. Wada, H. Toyoda, 2018

机译：改进的凝块波形分析，以测量抗因子IXA /因子X Bispecific抗体Emicizumab存在的血浆凝固电位：评论
8. Cell Penetrating Bispecific Antibodies for Targeting Oncogenic Transcription Factors in Advanced Prostate Cancer. [R] . Lilly, M., Weisbart, R. 2016

机译：细胞穿透双特异性抗体靶向晚期前列腺癌的致癌转录因子。

Novel Insights and New Developments Regarding Coagulation Revealed by Studies of the Anti-Factor IXa (Activated Factor IX)/Factor X Bispecific Antibody, Emicizumab

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