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Stx2e Novel Stx2e epitope protein and vaccine composition comprising the same

机译:Stx2e新型Stx2e表位蛋白和包含该蛋白的疫苗组合物

摘要

The present invention relates to a novel Stx2e epitope protein and a vaccine composition comprising the same. The recombinant epitope protein isolated from Stx2e secreted by Shiga toxin-producing E. coli (STEC) according to the present invention has no cytotoxicity, and has an excellent effect of producing an antibody having neutralization ability against Stx2e, thereby being effectively used as a composition for vaccines and feeds for preventing edema disease of swine.
机译:本发明涉及新的Stx2e表位蛋白和包含该表位蛋白的疫苗组合物。从本发明的产志贺毒素的大肠杆菌(STEC)分泌的Stx2e中分离的重组表位蛋白没有细胞毒性,并且具有产生对Stx2e具有中和能力的抗体的优异效果,因此可以有效地用作组合物用于预防猪水肿疾病的疫苗和饲料。

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