首页> 外国专利> Pharmaceutical composition for use in preventing or treating osteoporosis containing eucalyptol as an active ingredient

Pharmaceutical composition for use in preventing or treating osteoporosis containing eucalyptol as an active ingredient

机译:用于预防或治疗骨质疏松症的药物组合物,其含有桉油精作为有效成分

摘要

The present invention relates to a pharmaceutical composition containing eucalyptol or a pharmaceutically acceptable derivative thereof as an active component. The pharmaceutical composition according to the present invention has an effect of promoting the differentiation of osteoblasts by increasing an expression ratio of Id1, Dlx5, Runx2, ALP, and OC, which are osteoblast differentiation marker genes, and increasing calcification of the osteoblasts, thereby being able to be widely used as a medicine or health food for preventing or treating osteoporosis. Furthermore, the pharmaceutical composition increases activity of osteoblasts, rather than targeting osteoclasts, thereby being able to fundamentally treat osteoporosis through the promotion of osteogenesis and being able to exhibit an effect of preventing secondary fracture.
机译:药物组合物本发明涉及一种药物组合物,其含有桉油精或其药学上可接受的衍生物作为活性成分。根据本发明的药物组合物具有通过增加作为成骨细胞分化标记基因的Id1,Dlx5,Runx2,ALP和OC的表达比例并增加成骨细胞钙化从而促进成骨细胞分化的作用。能够广泛用作预防或治疗骨质疏松症的药物或保健食品。此外,该药物组合物增加了成骨细胞的活性,而不是靶向破骨细胞,从而能够通过促进成骨作用从根本上治疗骨质疏松症,并能够发挥防止继发性骨折的作用。

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