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Pharmaceutical composition for use in preventing or treating osteoporosis containing eucalyptol as an active ingredient

机译:用于预防或治疗骨质疏松症的药物组合物,其含有桉油精作为有效成分

摘要

The present invention relates to a pharmaceutical composition comprising eucalyptol or a pharmaceutically acceptable derivative thereof as an active ingredient. The pharmaceutical composition according to the present invention is characterized in that the osteoblast differentiation marker genes Id1, Dlx5, Runx2, ALP, OC And the osteoblast differentiation is promoted by increasing the expression level of osteoblast and increasing the calcification of osteoblast. Thus, it can be widely used as a medicine or a health food for the prevention or treatment of osteoporosis. In addition, rather than targeting osteoclasts, osteoblast activity can be increased to promote osteogenesis, thereby osteoporosis can be fundamentally treated, and secondary osteoporosis can be effectively prevented.
机译:本发明涉及一种药物组合物,其包含桉油精或其药学上可接受的衍生物作为活性成分。根据本发明的药物组合物的特征在于成骨细胞分化标记基因Id1,Dlx5,Runx2,ALP,OC,并且通过增加成骨细胞的表达水平和增加成骨细胞的钙化来促进成骨细胞分化。因此,它可以广泛地用作预防或治疗骨质疏松症的药物或保健食品。另外,除了靶向破骨细胞之外,可以增加成骨细胞活性以促进成骨,从而可以从根本上治疗骨质疏松症,并且可以有效地预防继发性骨质疏松症。

著录项

  • 公开/公告号KR101984541B1

    专利类型

  • 公开/公告日2019-05-31

    原文格式PDF

  • 申请/专利权人 대구대학교 산학협력단;

    申请/专利号KR20170139074

  • 发明设计人 장원구;

    申请日2017-10-25

  • 分类号A61K31/35;A23L33/10;

  • 国家 KR

  • 入库时间 2022-08-21 11:48:28

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