Rg3 COMPOSITION FOR INDUCING MATURATION OF NEXT-GENERATION DENDRITIC CELL COMPRISING GINSENOSIDE Rg3 AND METHOD FOR PRODUCING NEXT-GENERATION DENDRITIC CELL USING THE SAME

摘要

The present invention relates to a composition for inducing maturation into next generation dendritic cells containing ginsenoside Rg3 as an active component and a method for manufacturing mature next generation dendritic cells using the same. The composition for inducing dendritic cell maturation containing ginsenoside Rg3 of the present invention as the active component induces CD141 and Clec9a expression, and IP-10 cytokine secretion of immature human dendritic cells, increases the secretion of IL-12p70 and IFN-γ involved in the induction of anti-cancer immune functions, thereby being able to be usefully used for manufacturing next generation dendritic cells of CD141 +, Clec9a + subtypes, excellent in anti-cancer immunity.