PHAMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF THROMBOSIS COMPRISING KYUNG-OK-GO ADDING THE SILK OF ZEA MAYS AND PUMPKIN AND HEALTH FUNCTIONAL FOOD COMPRISING THE SAME

摘要

The present invention relates to a use of a restorative herb medicine prepared by adding Silk of Zea mays Linne and Cucurbita moschata. More specifically, the present invention relates to a pharmaceutical composition and health functional food for preventing or treating/ameliorating thrombosis through strong blood coagulation enzyme/factor inhibiting activity and platelet aggregation inhibiting activity by adding Silk of Zea mays Linne and Cucurbita moschata to an existing restorative herb medicine comprising Rehmannia glutinosa var. purpurea, Poria cocos, ginseng and honey as main ingredients. As being proved through an embodiment of the present specification, a restorative herb medicine having a Silk of Zea mays Linne and Cucurbita moschata as an active ingredient of a pharmaceutical composition and health functional food of the present invention: has excellent appealability by adding Silk of Zea mays Linne and Cucurbita moschata; exhibits strong antithrombotic activity by inhibiting thrombogenesis-related enzymes and blood coagulation factors; does not show hemolytic activity to human red blood cells at all; has excellent thermal stability; and does not exhibit loss in effects of inhibiting the thrombogenesis-related enzymes and the blood coagulation factors even at an acidic condition of pH 2 and within blood plasma at the same time such that the present invention is expected to be used for prevention and treatment of thrombosis such as ischemic stroke and hemorrhagic stroke through improvement of blood circulation. In addition, the active ingredient is processed into various forms such as extract, powder, pill, tablet, and the like to be taken at any time. Accordingly, the present invention is extremely useful in pharmaceutical and food industries.