Cargo-switching dissociable nanobiomaterial for treatment of atherosclerosis

摘要

The present invention relates to a cargo-switching dissociable nanobiomaterial for treating atherosclerosis, wherein cyclodextrin or a cyclodextrin derivative, and a complex of a complex of a statin-based compound of the present invention decompose cholesterol crystals by substituting cholesterol and statins from cholesterol crystals, are absorbed into macrophages and foam cells to induce apoptosis to inhibit atherogenesis and regress atherosclerotic plaques, thereby being able to be usefully used for preventing or treating atherosclerosis.