首页> 外国专利> Biodegradable anisotropic nanoparticles based on stereocomplexes between enantiomeric polylactides for controlled release of multiple drugs and methods of preparing thereof

Biodegradable anisotropic nanoparticles based on stereocomplexes between enantiomeric polylactides for controlled release of multiple drugs and methods of preparing thereof

机译:基于对映体聚丙交酯之间的立体配合物的可生物降解的各向异性纳米粒子,用于控制多种药物的释放及其制备方法

摘要

The present invention relates to a first compartment comprising an A block comprising a polymer exhibiting optical isomerism and an ABA block copolymer comprising a B block comprising polyethylene glycol (PEG); And a stereocomplex formed between the optical isomers of the ABA type block copolymer; The drug delivery system comprising an anisotropic nanostructure and a drug delivery system in which the drug is incorporated in each compartment.
机译:本发明涉及第一隔室,该第一隔室包括:包含显示出光学异构性的聚合物的A嵌段;和包含包含聚乙二醇(PEG)的B嵌段的ABA嵌段共聚物;并且在ABA型嵌段共聚物的旋光异构体之间形成立体络合物。该药物输送系统包括各向异性的纳米结构和药物输送系统,其中将药物掺入每个隔室中。

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