首页> 外国专利> MG4231 MG4244 Lactobacillus fermentum MG4231 or MG4244 having antiobesity activity derived from human and composition comprising the same

MG4231 MG4244 Lactobacillus fermentum MG4231 or MG4244 having antiobesity activity derived from human and composition comprising the same

机译:具有源自人类的抗肥胖活性的发酵乳杆菌MG4231或MG4244及其组合物

摘要

The present invention relates to: human-derived Lactobacillus fermentum MG4231 or Lactobacillus fermentum MG4244; and a pharmaceutical composition and a food composition, a quasi-drug composition, and health functional food which are to prevent or treat obesity-related diseases by having the same as active components. The lactobacillus fermentum MG4231 strain or MG4244 strain of the present invention: shows anti-obesity activity which suppresses the activity of lipase enzyme, the differentiation of preadipocytes, and the accumulation of triglyceride; has excellent ability to form colonies on the epithelial cells of digestive tracts due to a good self-aggregating ability; has resistance to acids and bile salts; and thus, can be used for a pharmaceutical composition, a food composition, a quasi-drug composition, and health functional food in various ways to treat and prevent obesity-related diseases.
机译:本发明涉及人源发酵乳杆菌MG4231或发酵乳杆菌MG4244。以及通过具有与活性成分相同的成分来预防或治疗与肥胖有关的疾病的药物组合物和食品组合物,准药物组合物以及保健功能食品。本发明的发酵乳杆菌MG4231菌株或MG4244菌株显示出抑制脂肪酶活性,前脂肪细胞分化和甘油三酸酯蓄积的抗肥胖活性。由于具有良好的自聚集能力,因此具有在消化道上皮细胞上形成菌落的能力。具有抗酸和胆盐的能力;因此,可以各种方式用于治疗和预防肥胖相关疾病的药物组合物,食品组合物,准药物组合物和保健功能食品。

著录项

  • 公开/公告号KR101981333B1

    专利类型

  • 公开/公告日2019-05-23

    原文格式PDF

  • 申请/专利权人 MEDIOGEN;PAEK NAM SOO;

    申请/专利号KR20180132240

  • 发明设计人 PAEK NAM SOO;KANG CHANG HO;

    申请日2018-10-31

  • 分类号C12N1/20;A23L33/135;A61K35/747;A61P3/04;C12R1/225;

  • 国家 KR

  • 入库时间 2022-08-21 11:48:34

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