--- Succinate-poly-caprolactone-succinate Polymers Self-assembled Drug Delivery Nanoparticles Made thereby and Composition Comprising the Same

摘要

The present invention relates to succinate-PCL-succinate (snPCL) represented by the following formula (1) wherein succinate is covalently bonded to both ends of poly (ε-caprolactone; Polymer, snPCL nanoparticles prepared therefrom, and anticancer or nano drug delivery compositions comprising the snPCL nanoparticles, wherein the snPCL polymer synthesized in the dumbbell shape forms nanoparticles through self-assembly in an aqueous phase, and the thus formed snPCL nanoparticles Can act as a nano-anti-cancer drug that can selectively kill cancer cells, and can also deliver drugs into cells by encapsulating various drugs, thereby enhancing normal cell function or inducing the death of cancer cells; [Chemical Formula 1] In Formula 1, n is 3 to 30.