首页> 外国专利> TP53 Method for detecting genes related with TP53 mutation gene and selected marker compositions for predicting gastric cancer prognostication or drug reactivity by the same method

TP53 Method for detecting genes related with TP53 mutation gene and selected marker compositions for predicting gastric cancer prognostication or drug reactivity by the same method

机译:TP53检测与TP53突变基因相关的基因的方法和用于预测胃癌预后或药物反应性的所选标记物的方法

摘要

Accordingly, the present invention provides a method for screening a gene statistically significantly associated with a TP53 mutant gene, a marker composition for predicting the prognosis or drug responsiveness of a selected gastric cancer by the method, and a preparation for detecting the mutation thereof Compositions and kits for predicting prognosis or drug reactivity, and methods of predicting the prognosis or drug responsiveness of gastric cancer using the marker compositions. The present invention has the advantage of being able to quickly and accurately predict the prognosis or drug responsiveness of gastric cancer and to determine the appropriate treatment direction according to the predicted prognosis or the result of drug response, thereby greatly contributing to the reduction of mortality due to stomach cancer.
机译:因此,本发明提供了筛选与统计学上显着相关的与 TP53 突变基因相关的基因的方法,通过该方法预测所选择的胃癌的预后或药物反应性的标志物组合物以及制备方法。用于检测其突变的组合物和用于预测预后或药物反应性的试剂盒,以及使用标志物组合物预测胃癌的预后或药物反应性的方法。本发明的优点是能够快速而准确地预测胃癌的预后或药物反应性,并根据预测的预后或药物反应的结果确定合适的治疗方向,从而极大地有助于降低由于胃癌引起的死亡率。胃癌。

著录项

  • 公开/公告号KR101999895B1

    专利类型

  • 公开/公告日2019-07-15

    原文格式PDF

  • 申请/专利权人 국립암센터;

    申请/专利号KR20170105375

  • 发明设计人 남승윤;박성진;김연희;임승묵;

    申请日2017-08-21

  • 分类号C12Q1/68;

  • 国家 KR

  • 入库时间 2022-08-21 11:48:10

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