首页> 外国专利> Composition for improving skin winkle or enhancing skin elasticity and for preventing improving or treating acne containing Sedum takesimense Nakai extract or compound isolated therefrom

Composition for improving skin winkle or enhancing skin elasticity and for preventing improving or treating acne containing Sedum takesimense Nakai extract or compound isolated therefrom

机译:用于改善皮肤皱纹或增强皮肤弹性并防止改善或治疗痤疮的组合物,所述组合物包含景天景天提取物或从中分离出的化合物

摘要

The present invention relates to a composition for improving skin wrinkles or enhancing skin elasticity and a composition for preventing, improving or treating acne, including sagirincho extract or a compound separated therefrom. Or 4,6-di-O-galloyl-albutin, 2,4,6-tri-O-galloyl-beta-glucose (2,4,6-tri- O-galloyl-β-glucose), 1,2,4,6-tetra-O-galloyl-beta-glucose (1,2,4,6-tetra-O-galloyl-β-glucose) and salts thereof It relates to a composition for improving skin wrinkles or improving skin elasticity and a composition for preventing, improving or treating acne containing any one or two or more compounds selected from the group consisting of. The composition of the present invention can be safely applied to the human body by containing an island extract, or a compound isolated therefrom as an active ingredient, promotes collagen biosynthesis of skin cells, inhibits the expression of collagenase involved in collagen degradation In addition to suppressing the elastase activity involved in elastin degradation, it is also effective in inhibiting hyaluronic acid biosynthesis gene expression and hyaluronidase inhibition, which are important for skin moisturization, and having estrogen receptor binding activity for better skin wrinkle improvement and skin It may have an elasticity enhancing effect. In addition, the composition of the present invention has excellent anti-inflammatory and antibacterial activity against acne causing bacteria can effectively prevent, improve or treat acne.
机译:本发明涉及用于改善皮肤皱纹或增强皮肤弹性的组合物,以及用于预防,改善或治疗痤疮的组合物,所述组合物包括sagirincho提取物或从其分离的化合物。或4,6-二-O- Galloyl-albutin,2,4,6-三-O-galloyl-β-葡萄糖(2,4,6-三-O-galloyl-β-葡萄糖),1,2, 4,6-四-O-galloyl-β-葡萄糖(1,2,4,6-四-O-galloyl-β-葡萄糖)及其盐涉及改善皮肤皱纹或改善皮肤弹性的组合物,用于预防,改善或治疗痤疮的组合物,其包含选自以下组的任何一种或两种或更多种化合物。本发明的组合物可以通过包含岛提取物或从岛提取物中分离的化合物作为有效成分而安全地应用于人体,促进皮肤细胞的胶原生物合成,抑制与胶原降解有关的胶原酶的表达。弹性蛋白的活性与弹性蛋白降解有关,它还可以有效抑制透明质酸生物合成基因的表达和透明质酸酶的抑制,这对皮肤保湿很重要,并且具有雌激素受体结合活性,可以更好地改善皮肤皱纹和皮肤。它可能具有增强弹性的作用。另外,本发明的组合物具有优异的抗痤疮的抗炎和抗菌活性,可有效预防,改善或治疗痤疮。

著录项

  • 公开/公告号KR102015452B1

    专利类型

  • 公开/公告日2019-08-28

    原文格式PDF

  • 申请/专利权人 주식회사 다인소재;

    申请/专利号KR20180084298

  • 申请日2018-07-19

  • 分类号A61K8/97;A23L33/105;A61K31/7034;A61K36/41;A61K8/60;A61Q19/08;

  • 国家 KR

  • 入库时间 2022-08-21 11:47:53

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