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CRIF1 Composition for Inhibition or Treatment of Keloids and Hypertrophic Scar Comprising CRIF1 Antagonist

机译:用于抑制或治疗瘢痕loid和肥厚性瘢痕的CRIF1组合物,其包含CRIF1拮抗剂。

摘要

The present invention relates to compositions that are effective in inhibiting or treating the formation of keloids and hypertrophic scars by inhibiting proliferation and neovascularization, cell migration and ECM production. More particularly, CRIF1 (CR6 interacting) Factor 1) relates to a pharmaceutical composition for inhibiting or treating keloid and hypertrophic scar formation comprising an inhibitor of gene expression or an inhibitor of activity of CRIF1 protein as an active ingredient.
机译:本发明涉及通过抑制增殖和新血管形成,细胞迁移和ECM产生而有效抑制或治疗瘢痕loid和肥大性瘢痕形成的组合物。更特别地,CRIF1(与CR6相互作用)因子1)涉及用于抑制或治疗瘢痕loid和肥厚性瘢痕形成的药物组合物,其包含基因表达抑制剂或CRIF1蛋白活性抑制剂作为活性成分。

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