METHOD OF MODELING NEURODEGENERATIVE DISEASES IN ADULT LABORATORY RODENTS

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine, namely to experimental medicine. Capsaicin solution is administered. Capsaicin solution is administered intraperitoneally under general anesthesia, in a total dose of 100 to 110 mg of capsaicin per 1 kg of animal weight, three times: 25–35 mg/kg the 1^st and 2^nd day, and 40–45 mg/kg the 3^rd day.;EFFECT: method allows to model a long-term neurodystrophic process in adult rats, which is similar to that in humans, which is necessary for developing treatment methods and evaluating their effectiveness.;1 cl, 2 ex, 1 tbl