, R1 is hydrogen, methyl or -(CH2)2OR3, R2 is methyl or -(CH2)2OR4, or R1 and R2, together with the nitrogen atom to which they are attached, are associated with the formation of 5- or 6-membered heterocyclyl, wherein the 6-membered heterocyclyl is optionally substituted with two hydroxy substituents; each of R3 and R4 independently represents hydrogen or methyl; and n is an integer having a value of 5 or 6.;EFFECT: said compound has the activity inducers of interferon alpha (IFN-α) and can be used to treat or prevent an allergic reaction, an inflammatory condition, an infectious disease or cancer.;11 cl, 10 ex"/> PYRROLO3,2-DPYRIMIDINE DERIVATIVES AS INDUCERS OF HUMAN INTERFERON
首页> 外国专利> PYRROLO3,2-DPYRIMIDINE DERIVATIVES AS INDUCERS OF HUMAN INTERFERON

PYRROLO3,2-DPYRIMIDINE DERIVATIVES AS INDUCERS OF HUMAN INTERFERON

机译:吡咯并[3,2-D]嘧啶衍生物作为人干扰素的诱导剂

摘要

FIELD: chemistry.;SUBSTANCE: invention relates to a novel compound of formula (I) and a pharmaceutically acceptable salt thereof. In formula (I) , R1 is hydrogen, methyl or -(CH2)2OR3, R2 is methyl or -(CH2)2OR4, or R1 and R2, together with the nitrogen atom to which they are attached, are associated with the formation of 5- or 6-membered heterocyclyl, wherein the 6-membered heterocyclyl is optionally substituted with two hydroxy substituents; each of R3 and R4 independently represents hydrogen or methyl; and n is an integer having a value of 5 or 6.;EFFECT: said compound has the activity inducers of interferon alpha (IFN-α) and can be used to treat or prevent an allergic reaction, an inflammatory condition, an infectious disease or cancer.;11 cl, 10 ex
机译:技术领域本发明涉及式(I)的新型化合物及其药学上可接受的盐。在式(I)中,,R 1 是氢,甲基或-(CH 2 2 OR 3 ,R 2 是甲基或-(CH 2 2 OR 4 或R 1 和R 2 以及氮原子一起它们连接的与5-或6-元杂环基的形成有关,其中6-元杂环基任选地被两个羟基取代基取代; R 3 和R 4 分别独立地表示氢或甲基。 n是值为5或6的整数;效果:该化合物具有干扰素α(IFN-α)的活性诱导剂,可用于治疗或预防变态反应,炎症,传染病或癌症。; 11 cl,10前

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号