, R1 is hydrogen, methyl or -(CH2)2OR3, R2 is methyl or -(CH2)2OR4, or R1 and R2, together with the nitrogen atom to which they are attached, are associated with the formation of 5- or 6-membered heterocyclyl, wherein the 6-membered heterocyclyl is optionally substituted with two hydroxy substituents; each of R3 and R4 independently represents hydrogen or methyl; and n is an integer having a value of 5 or 6.;EFFECT: said compound has the activity inducers of interferon alpha (IFN-α) and can be used to treat or prevent an allergic reaction, an inflammatory condition, an infectious disease or cancer.;11 cl, 10 ex"/>
公开/公告号RU2676684C2
专利类型
公开/公告日2019-01-10
原文格式PDF
申请/专利号RU20160131189
发明设计人 BIGGADIKE KEITH (GB);CHAMPIGNY AURELIE CECILE (GB);COE DIANE MARY (GB);TAPE DANIEL TERENCE (GB);SMITH STEPHEN ALLAN (GB);
申请日2015-02-18
分类号C07D487/04;A61K31/519;A61P35;A61P29;A61P31/04;
国家 RU
入库时间 2022-08-21 11:46:24