METHOD FOR MANUFACTURING PHARMACEUTICAL COMPOSITION IN FORM OF EXTENDED-RELEASE TABLETS CONTAINING PIRFENIDONE AND USE THEREOF IN REGRESSION OF CHRONIC RENAL INSUFFICIENCY, BREAST CAPSULAR CONTRACTURE AND HEPATIC FIBROSIS IN HUMANS

摘要

FIELD: medicine; pharmaceuticals.;SUBSTANCE: present invention relates to a pharmaceutical composition in the form of a sustained release tablet containing from 100 to 600 mg of Pirfenidone (PFD), in which the drug is bioavailable for an extended period of time lasting 12 hours from the administration thereof.;EFFECT: present invention provides a higher therapeutic effectiveness compared with other pharmaceutical forms of pirfenidone for oral administration.;8 cl, 6 dwg, 6 tbl