CHROMINE DERIVATIVE AS DOPAMINE D3 RECEPTOR ANTAGONIST FOR APPLICATION IN TREATING AUTISM SPECTRUM DISORDER

摘要

FIELD: chemical-pharmaceutical industry.;SUBSTANCE: group of inventions relates to use of a chromone derivative. Disclosed are: use of N-(3-{4-[4-(8-oxo-8H-[1,3]dioxolo[4,5-g]chromene-7-yl)-butyl]-piperazin-1-yl}-phenyl)methanesulphonamide or a pharmaceutically acceptable salt thereof as a medicament for treating a social interaction deficiency associated with an autism spectrum disorder, and a pharmaceutical composition of the same purpose based thereon.;EFFECT: technical result is a compound which represents a dopamine D3 receptor antagonist, eliminates the deficiency of social interactions caused by the prenatal action of sodium valproate.;4 cl, 1 dwg, 2 ex