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SELF MICRO-EMULSIFYING ORAL PHARMACEUTICAL COMPOSITION OF HYDROPHILIC DRUG AND PREPARATION METHOD THEREOF

机译:自微乳化亲水药物的口服药物成分及其制备方法

摘要

A self micro-emulsifying oral pharmaceutical composition of a hydrophilic drug or its pharmaceutical acceptable salt and the preparation method thereof are disclosed. The composition comprises hydrophilic drug such as bendamustine or gemcitabine, solvent, surfactant and hydrophilic carrier, and has good bioavailability and stability. Said hydrophilic carrier is compatible with drug solution and surfactant.
机译:公开了一种亲水性药物或其药学上可接受的盐的自微乳化口服药物组合物及其制备方法。该组合物包含亲水性药物如苯达莫司汀或吉西他滨,溶剂,表面活性剂和亲水性载体,并具有良好的生物利用度和稳定性。所述亲水性载体与药物溶液和表面活性剂相容。

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