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SINGLE MOLECULE SEQUENCING AND UNIQUE MOLECULAR IDENTIFIERS TO CHARACTERIZE NUCLEIC ACID SEQUENCES

机译:单分子测序和独特的分子标识符,可表征核酸序列

摘要

Embodiments of a method and/or system (e.g., for improved single molecule sequencing, etc.) can include preparing a set of unique molecular identifier (UMI)-based molecules associated with a set of target nucleic acid sequences; facilitating generation of (e.g., generating, etc.) a set of tagged nucleic acid molecules based on the set of UMI-based molecules and a set of nucleic acid molecules corresponding to (e.g., including, etc.) the set of target nucleic acid sequences; and/or facilitating (e.g., performing, etc.) single molecule sequencing with the set of tagged nucleic acid molecules.
机译:方法和/或系统的实施例(例如,用于改进的单分子测序等)可以包括准备与一组靶核酸序列相关的一组基于独特分子识别符(UMI)的分子;基于该组基于UMI的分子和与该目标核酸组相对应的(例如,包括等)的一组核酸分子,促进一组标记核酸分子的生成(例如,生成等)顺序;和/或促进(例如进行等)用该组标记的核酸分子进行单分子测序。

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