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Iron oxide nanoparticles doped with a giant self-generating alkali metal or alkaline earth metal in a biocompatible alternating magnetic field and a method for producing the same.
Iron oxide nanoparticles doped with a giant self-generating alkali metal or alkaline earth metal in a biocompatible alternating magnetic field and a method for producing the same.
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机译:在生物相容性交变磁场中掺杂有巨大的自生碱金属或碱土金属的氧化铁纳米颗粒及其制备方法。
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摘要
Disclosed herein are iron oxide nanoparticles prepared through high-temperature thermal decomposition of an Fe3+ precursor and an M+ or M2+ (M=Li, Na, K, Mg, and Ca) precursor in an oxygen atmosphere. The iron oxide nanoparticles are nanoparticles, in which an alkali metal or alkali earth metal is doped into an Fe vacancy site of γ-Fe2O3, and generate explosive heat even in a biocompatible low AC magnetic field. Through both in vitro and in vivo tests, it was proven that cancer cells could be killed by performing low-frequency hyperthermia using the iron oxide nanoparticles set forth above.
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