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Adrenomedullin to guide therapy of blood pressure decline

机译:肾上腺髓质素指导降压治疗

摘要

Subject matter of the present invention is an in vitro method for identifying a subject in need of administration of fluid resuscitation or a vasopressor comprising the following steps:Determining the level of proADM and/or fragments thereof having at least 6 amino acids in a bodily fluid of said subjectCorrelating said level with the need of said patient for fluid resuscitation or administration of a vasopressor wherein said patient is identified as having such a need if the level of proADM and/or fragments thereof having at least 6 amino acids in the bodily fluid of said subject is above a threshold.
机译:本发明的主题是一种用于识别需要进行液体复苏或升压治疗的对象的体外方法,包括以下步骤: 确定所述受试者的体液中的proADM和/或其具有至少6个氨基酸的片段的水平 关联所述所述患者需要进行液体复苏或给予血管加压药的水平,其中如果所述受试者的体液中的proADM和/或其片段具有至少6个氨基酸的水平高于上述患者,则将所述患者鉴定为具有这种需要阈值。

著录项

  • 公开/公告号US10598674B2

    专利类型

  • 公开/公告日2020-03-24

    原文格式PDF

  • 申请/专利权人 SPHINGOTEC GMBH;

    申请/专利号US201414778114

  • 发明设计人 ANDREAS BERGMANN;

    申请日2014-03-19

  • 分类号A61K39/395;C07K16/26;G01N33/68;G01N33/74;

  • 国家 US

  • 入库时间 2022-08-21 11:29:44

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