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IMPLANT WITH REACTIVE OXYGEN SPECIES SCAVENGING COATING

机译:活性氧物种消除涂层的注入

摘要

A chronically implanted medical device is disclosed that has an outermost layer formed from a conjugate of a polymer with lipoic acid, the conjugate having free 1,2-dithiolane groups. It is contemplated that this layer scavenges reactive oxygen species, i.e. acts as an antioxidant, and thus reduces inflammation and other adverse effects around the implant itself.
机译:公开了一种慢性植入的医疗装置,其具有由聚合物与硫辛酸的共轭物形成的最外层,该共轭物具有游离的1,2-二硫杂环戊酸酯基团。可以预期,该层清除了活性氧,即起抗氧化剂的作用,因此减少了植入物本身周围的炎症和其他不利影响。

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