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SYSTEMS AND METHODS FOR USING MACHINE LEARNING AND DNA SEQUENCING TO EXTRACT LATENT INFORMATION FOR DNA, RNA AND PROTEIN SEQUENCES
SYSTEMS AND METHODS FOR USING MACHINE LEARNING AND DNA SEQUENCING TO EXTRACT LATENT INFORMATION FOR DNA, RNA AND PROTEIN SEQUENCES
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机译:使用机器学习和DNA序列提取DNA,RNA和蛋白质序列的最新信息的系统和方法
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摘要
A method of characterizing biological sequences includes: preparing a library of sequences; subjecting the sequences in the library to at least one screening experiment to obtain an experiment outcome of each of the sequences; creating a first dataset comprising identities of the sequences and the experiment outcomes of the sequences; and training a first neural network using the first dataset to extract first sequence features from the sequences in the first dataset. A second neural network may be additionally be trained using a second dataset based on an external database to generate a pre-trained model, which is used extract additional features from the first dataset.
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