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DISPLAY OF MOLECULES ON SILENTLY GENETICALLY ENCODED NANOSCALE CARRIERS FOR DETERMINING SYNERGISTIC MOLECULAR INTERACTIONS
DISPLAY OF MOLECULES ON SILENTLY GENETICALLY ENCODED NANOSCALE CARRIERS FOR DETERMINING SYNERGISTIC MOLECULAR INTERACTIONS
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机译:分子在沉默基因编码的纳米载体上的显示,以测定协同分子相互作用
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摘要
The present application provides a method of producing a “liquid” array of ligand (such as glycan) modified bacteriophage where the ligand modification is encoded genetically within the bacteriophage genome. This method will allow for the determination of the ligand binding profile of biomacromolecules and cells. Furthermore the method allows the elucidation of ligand-protein interactions where ligand binding is co-operative and synergistic.
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