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Display of molecules on silently genetically encoded nanoscale carriers for determining synergistic molecular interactions
Display of molecules on silently genetically encoded nanoscale carriers for determining synergistic molecular interactions
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机译:在无声遗传编码的纳米级载体上显示分子,以确定协同分子相互作用
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摘要
The present application provides a method of producing a "liquid" array of ligand (such as glycan) modified bacteriophage where the ligand modification is encoded genetically within the bacteriophage genome. This method will allow for the determination of the ligand binding profile of biomacromolecules and cells. Furthermore the method allows the elucidation of ligand-protein interactions where ligand binding is co-operative and synergistic.
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